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Understanding clinical therapies on cognitive function is an important aspect of the drug discovery process. Objective cognitive testing (not based on self-reported measures) in early phase clinical trials could provide insight to subtle but important effects on a subject’s ability to perceive, process, understand and store information, make decisions and produce appropriate responses.

This understanding can benefit the drug discovery process by informing decisions to progress candidate compounds, dose-response relationships, selection of safe doses, detection of off-target effects and risk: benefit to the target indication.

Cognitive testing can be deployed at pre-screening to ensure you have appropriate participants on your study and in-study to assess compound effects on different cognitive domains such as:

  • Memory and recall 
  • Processing/reaction speed
  • Speech and language
  • Attention/Executive functions
  • Multitasking.

 

Contact us to discuss any cognitive testing you need for your clinical trial.

Services

The Science Behind CRS can help Sponsors and CROs with some of these challenges in Phase 1 trials by providing the tools and specialist expertise to answer key questions in relation to safety and efficacy when bringing novel drug candidates to human clinical trials.

Transcranial Magnetic Stimulation - Electro Diagnostic Markers
Electroencephalography & Electromyography